I have made this list as extensive as possible, but there may be something I have missed. Please note that these books are very light-hearted and while these things may be mentioned, they aren't described in hideous detail. 

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• loss of a loved one, death of a parent, death of a sibling

• manipulation, toxic relationship

• alcohol

• anxiety

• blood, mild injuries

• death, murder, death threats

• depression

• psychedelics (alien)

• guilt

• intrusive thoughts

• alien abduction

• needles

• police (alien robocops, bumbling)

• prostitution (just mentioned)

• suicidal thoughts (passive)

• torture (light)

• trauma, PTSD (not called that explicitly,)

• mild violence, gunshots, (laser) guns, physical assault

• war (just mentioned)